Title
Machine learning to predict extubation outcome in premature infants.
Abstract
Though treatment of the ventilated premature infant has experienced many advances over the past decades, determining the best time point for extubation of these infants remains challenging and the incidence of extubation failures largely unchanged. The objective was to provide clinicians with a decision-support tool to determine whether to extubate a mechanically ventilated premature infant by using a set of machine learning algorithms on a dataset assembled from 486 premature infants receiving mechanical ventilation. Algorithms included artificial neural networks (ANN), support vector machine (SVM), naïve Bayesian classifier (NBC), boosted decision trees (BDT), and multivariable logistic regression (MLR). Results for ANN, MLR, and NBC were satisfactory (area under the curve [AUC]: 0.63-0.76); however, SVM and BDT consistently showed poor performance (AUC ~0.5). Complex medical data such as the data set used for this study require further preprocessing steps before prediction models can be developed that achieve similar or better performance than clinicians.
Year
DOI
Venue
2013
10.1109/IJCNN.2013.6707058
IJCNN
Keywords
Field
DocType
area under the curve,auc,paediatrics,medical data,mlr,premature infants,boosted decision trees,machine learning algorithms,regression analysis,mechanically ventilated premature infant,artificial neural networks,decision-support tool,bdt,extubation outcome,svm,multivariable logistic regression,support vector machine,bayes methods,decision support systems,mechanical ventilation,ann,nbc,ventilation,extubation failures,medical computing,prediction models,decision trees,support vector machines,neural nets,naïve bayesian classifier,bioinformatics,biomedical research
Decision tree,Time point,Pattern recognition,Computer science,Support vector machine,Mechanical ventilation,Artificial intelligence,Predictive modelling,Artificial neural network,Logistic regression,Machine learning,Alternating decision tree
Conference
Volume
ISSN
ISBN
2013
2161-4393
978-1-4673-6128-6
Citations 
PageRank 
References 
2
0.39
2
Authors
4
Name
Order
Citations
PageRank
Martina Mueller151.87
Carol C Wagner220.39
Romesh Stanislaus3883.56
Jonas S Almeida473142.25