Title
Particle Detection on Election Microscopy Micrographs Using Multi-Classifier Systems
Abstract
The determination of the three-dimensional (3D) structure of biological macromolecules at different configurations can be very important for understanding biological processes at the molecular level. The detection of individual particles from electron microscopy (EM) micrographs turns into a major labor-intensive bottleneck, when the number of particles needed starts to exceed a few tens of thousand molecular images. Multi-classifier systems have been widely investigated as tools for performing complex classifying tasks. In this work, we investigate the adequacy of using multi-classifier systems to detect particles on electron microscopy micrographs. In order to do so, we compare the performance of five algorithms for generating individual classifiers and three other ones for multi-classifier algorithms. Such results are also compared with others found in the literature. In terms of results, the multi-classifier systems generated show larger accuracy (correct classification) and lower false positive and negative rates.
Year
DOI
Venue
2007
10.1109/HIS.2007.65
HIS
Keywords
Field
DocType
biological process,multi-classifier system,thousand molecular image,election microscopy,individual classifier,molecular level,particle detection,electron microscopy micrographs,multi-classifier algorithm,individual particle,multi-classifier systems,electron microscopy,biological macromolecule,macromolecules,three dimensional,molecular biophysics,indexing terms,image classification,molecular imaging,false positive
Bottleneck,Particle number,Biological system,Electron microscope,Molecular biophysics,Microscopy,Contextual image classification,Classifier (linguistics),Materials science,Particle
Conference
ISBN
Citations 
PageRank 
0-7695-2946-1
1
0.37
References 
Authors
1
5
Name
Order
Citations
PageRank
Lucas M. Oliveira1143.62
Raul B. Paradeda221.06
Bruno M. Carvalho318219.31
Anne M. P. Canuto439246.33
Marcilio C. P. de Souto510610.47