Title
ProbeSelect: selecting differentially expressed probes in transcriptional profile data.
Abstract
Transcriptional profiling still remains one of the most popular techniques for identifying relevant biomarkers in patient samples. However, heterogeneity in the population leads to poor statistical evidence for selection of most relevant biomarkers to pursue. In particular, human transcriptional differences can be subtle, making it difficult to tease out real differentially expressed biomarkers from the variability inherent in the population. To address this issue, we propose a simple statistical technique that identifies differentially expressed probes in heterogeneous populations as compared with controls.
Year
DOI
Venue
2014
10.1093/bioinformatics/btt720
BIOINFORMATICS
Field
DocType
Volume
Population,Data mining,Computer science,Profiling (computer programming),Bioinformatics,Java,Gene expression profiling
Journal
30
Issue
ISSN
Citations 
4
1367-4803
0
PageRank 
References 
Authors
0.34
0
5
Name
Order
Citations
PageRank
Raghavendra Hosur1211.84
Suzanne Szak200.34
Alice Thai300.34
Norm Allaire400.34
Jadwiga Bienkowska5121.94