Name
Title | ||
|---|---|---|
Consistency of parametric registration in serial MRI studies of brain tumor progression |
Abstract | ||
|---|---|---|
Object The consistency of parametric registration in multi-temporal magnetic resonance (MR) imaging studies was evaluated.
Materials and methods Serial MRI scans of adult patients with a brain tumor (glioma) were aligned by parametric registration. The performance of
low-order spatial alignment (6/9/12 degrees of freedom) of different 3D serial MR-weighted images is evaluated. A registration
protocol for the alignment of all images to one reference coordinate system at baseline is presented. Registration results
were evaluated for both, multimodal intra-timepoint and mono-modal multi-temporal registration. The latter case might present
a challenge to automatic intensity-based registration algorithms due to ill-defined correspondences. The performance of our
algorithm was assessed by testing the inverse registration consistency. Four different similarity measures were evaluated
to assess consistency.
Results Careful visual inspection suggests that images are well aligned, but their consistency may be imperfect. Sub-voxel inconsistency
within the brain was found for allsimilarity measures used for parametric multi-temporal registration. T1-weighted images
were most reliable for establishing spatial correspondence between different timepoints.
Conclusions The parametric registration algorithm is feasible for use in this application. The sub-voxel resolution mean displacement
error of registration transformations demonstrates that the algorithm converges to an almost identical solution for forward
and reverse registration. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1007/s11548-008-0234-5 | Int. J. Computer Assisted Radiology and Surgery |
Keywords | Field | DocType |
temporalmagneticresonancemrimagingstudieswaseva- luated. materials and methods serial mri scans of adult patients withabraintumorgliomawerealignedbyparametricregis- tration. the performance of low-order spatial alignment keywords inverse registration consistency · parametric serial mr image registration · tumor disease progression,magnetic resonance,coordinate system,visual inspection,degree of freedom | Brain tumor,Parametric statistics,Radiology,Medicine,Magnetic resonance imaging | Journal |
Volume | Issue | ISSN |
3 | 3 | 1861-6429 |
Citations | PageRank | References |
2 | 0.41 | 11 |
Authors | ||
11 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Andreas Mang | 1 | 35 | 10.57 |
| Julia A Schnabel | 2 | 1978 | 151.49 |
| William R Crum | 3 | 448 | 32.49 |
| Marc Modat | 4 | 898 | 72.33 |
| Oscar Camara-Rey | 5 | 18 | 3.03 |
| Christoph Palm | 6 | 58 | 8.33 |
| Gisele Brasil Caseiras | 7 | 2 | 0.41 |
| H. Rolf Jäger | 8 | 13 | 3.17 |
| Sébastien Ourselin | 9 | 2499 | 237.61 |
| Thorsten M. Buzug | 10 | 518 | 81.29 |
| David J. Hawkes | 11 | 4262 | 470.26 |