Title
Studying brain morphometry using conformal equivalence class
Abstract
Two surfaces are conformally equivalent if there exists a bijective angle-preserving map between them. The Teichmüller space for surfaces with the same topology is a finite-dimensional manifold, where each point represents a conformal equivalence class, and the conformal map is homotopic to the identity map. In this paper, we propose a novel method to apply conformal equivalence based shape index to study brain morphometry. The shape index is defined based on Teichmüller space coordinates. It is intrinsic, and invariant under conformal transformations, rigid motions and scaling. It is also simple to compute; no registration of surfaces is needed. Using the Yamabe flow method, we can conformally map a genus-zero open boundary surface to the Poincaré disk. The shape indices that we compute are the lengths of a special set of geodesics under hyperbolic metric. By computing and studying this shape index and its statistical behavior, we can analyze differences in anatomical morphometry due to disease or development. Study on twin lateral ventricular surface data shows it may help detect generic influence on lateral ventricular shapes. In leave-one-out validation tests, we achieved 100% accurate classification (versus only 68% accuracy for volume measures) in distinguishing 11 HIV/AIDS individuals from 8 healthy control subjects, based on Teichmüller coordinates for lateral ventricular surfaces extracted from their 3D MRI scans.Our conformal invariants, the Teichmüller coordinates, successfully classified all lateral ventricular surfaces, showing their promise for analyzing anatomical surface morphometry.
Year
DOI
Venue
2009
10.1109/ICCV.2009.5459416
ICCV
Keywords
DocType
Volume
anatomical morphometry,teichmilller coordinates,genus-zero open boundary surface,leave-one-out validation tests,diseases,statistical analysis,lateral ventricular surface data,brain morphometry,conformal equivalence based 3d shape index,biomedical mri,disease,hyperbolic metric,conformal transformations,rigid motions,3d mri scans,yamabe flow method,conformal equivalence class,anatomical surface morphometry,medical computing,poincare disk,hiv-aids individuals,teichmilller space coordinates,brain models,lateral ventricular shapes,healthy control subjects,shape,face,indexation,topology,conformal map,measurement
Conference
2009
Issue
ISSN
ISBN
1
1550-5499 E-ISBN : 978-1-4244-4419-9
978-1-4244-4419-9
Citations 
PageRank 
References 
1
0.36
11
Authors
7
Name
Order
Citations
PageRank
Yalin Wang1104279.53
Wei Dai210.36
Yi-Yu Chou329022.25
Xianfeng Gu42997189.71
Tony F. Chan58733659.77
Arthur W. Toga63128261.46
Paul Thompson73860321.32