Paper Info
Title
Novel application of a multiscale entropy index as a sensitive tool for detecting subtle vascular abnormalities in the aged and diabetic.
Abstract
Although previous studies have shown the successful use of pressure-induced reactive hyperemia as a tool for the assessment of endothelial function, its sensitivity remains questionable. This study aims to investigate the feasibility and sensitivity of a novel multiscale entropy index (MEI) in detecting subtle vascular abnormalities in healthy and diabetic subjects. Basic anthropometric and hemodynamic parameters, serum lipid profiles, and glycosylated hemoglobin levels were recorded. Arterial pulse wave signals were acquired from the wrist with an air pressure sensing system (APSS), followed by MEI and dilatation index (DI) analyses. MEI succeeded in detecting significant differences among the four groups of subjects: healthy young individuals, healthy middle-aged or elderly individuals, well-controlled diabetic individuals, and poorly controlled diabetic individuals. A reduction in multiscale entropy reflected age- and diabetes-related vascular changes and may serve as a more sensitive indicator of subtle vascular abnormalities compared with DI in the setting
Year
DOI
Venue
2013
10.1155/2013/645702
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE
Keywords
Field
DocType
anthropometry,entropy,aging,case control studies,blood pressure,diabetes mellitus,algorithms,young adult,hemodynamics
Multiscale entropy,Sensing system,Young adult,Blood pressure,Artificial intelligence,Medicine,Hemodynamics,Computer vision,Diabetes mellitus,Arterial pulse,Case-control study,Internal medicine,Cardiology,Endocrinology
Journal
Volume
ISSN
Citations 
2013
1748-670X
2
PageRank 
References 
Authors
0.51
2
5
Name
Order
Citations
PageRank
Hsien-Tsai Wu124230.90
Men-Tzung Lo28313.65
Guan-Hong Chen321.19
Cheuk-Kwan Sun46510.19
Jian-Jung Chen5162.03