Title
Spatiotemporal patterning of uterine excitation patterns in human labour.
Abstract
The mechanisms leading to the initiation of normal, premature or dysfunctional human labour are poorly understood, as animal models are inappropriate, and experimental studies are limited. Computational modelling provides a means of linking non-invasive clinical data with the results of in vitro cell and tissue physiology. Nonlinear wave processes – propagation in an excitable medium – provides a quantitatively testable description of mechanisms of premature and full term labour, and a view of changes in uterine electrophysiology during gestation as a trajectory in excitation and intercellular coupling parameter space. Propagation phenomena can account for both premature and full term labour.
Year
DOI
Venue
2013
10.1016/j.biosystems.2013.03.012
Biosystems
Keywords
Field
DocType
Computational biology,Uterus,Pregnancy,Birth
Neuroscience,Excitable medium,Biology,Internal medicine,Artificial intelligence,Endocrinology,Machine learning
Journal
Volume
Issue
ISSN
112
2
0303-2647
Citations 
PageRank 
References 
1
0.40
1
Authors
2
Name
Order
Citations
PageRank
Eleftheria Pervolaraki111.42
Arun V. Holden25220.71