Title
Three-dimensional diffusion tensor magnetic resonance microimaging of adult mouse brain and hippocampus.
Abstract
The use of diffusion tensor information as an additional contrast in MR microimaging was investigated in ex vivo mouse brain and isolated hippocampus. Diffusion Tensor Imaging (DTI) provided unique contrast to identify many internal structures of the gray matter such as hippocampus, thalamus, and cortex. In hippocampus, stratum granulosum and stratum pyramidale could be identified using the isotropic water diffusion constant. Stratum moleculare and stratum radiatum were identified from their characteristic fiber architecture revealed by color-coded DTI. Identification of these structures allowed reconstruction of their 3-D volume. Thus, high-resolution DTI has excellent potential as a tool for 3-D characterization of murine brains.
Year
DOI
Venue
2002
10.1006/nimg.2001.1012
NeuroImage
Keywords
DocType
Volume
DTI,mouse,brain,hippocampus
Journal
15
Issue
ISSN
Citations 
4
1053-8119
26
PageRank 
References 
Authors
8.44
0
3
Name
Order
Citations
PageRank
Jiangyang Zhang141724.76
Peter C M van Zijl2268.44
Susumu Mori3268.44