Abstract | ||
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The mechanisms leading to the initiation of normal, premature or dysfunctional human labour are poorly understood, as animal models are inappropriate, and experimental studies are limited. Computational modelling provides a means of linking non-invasive clinical data with the results of in vitro cell and tissue physiology. Nonlinear wave processes --- propagation in an excitable medium --- provides a quantitatively testable description of mechanisms of premature and full term labour, and a view of changes in uterine electrophysiology during gestation as a trajectory in excitation and intercellular coupling parameter space. Propagation phenomena can account for both premature and full term labour. |
Year | DOI | Venue |
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2012 | 10.1007/978-3-642-28792-3_21 | IPCAT |
Keywords | Field | DocType |
computational modelling,non-invasive clinical data,dysfunctional human labour,nonlinear wave process,full term labour,excitable medium,human uterine excitation pattern,experimental study,intercellular coupling parameter space,animal model,propagation phenomenon | Neuroscience,Synchronization,Excitable medium,Biology,Internal medicine,Excitation,Endocrinology | Conference |
Citations | PageRank | References |
0 | 0.34 | 1 |
Authors | ||
2 |
Name | Order | Citations | PageRank |
---|---|---|---|
Eleftheria Pervolaraki | 1 | 1 | 1.42 |
Arun V. Holden | 2 | 52 | 20.71 |