Title
Human uterine excitation patterns leading to labour: synchronization or propagation?
Abstract
The mechanisms leading to the initiation of normal, premature or dysfunctional human labour are poorly understood, as animal models are inappropriate, and experimental studies are limited. Computational modelling provides a means of linking non-invasive clinical data with the results of in vitro cell and tissue physiology. Nonlinear wave processes --- propagation in an excitable medium --- provides a quantitatively testable description of mechanisms of premature and full term labour, and a view of changes in uterine electrophysiology during gestation as a trajectory in excitation and intercellular coupling parameter space. Propagation phenomena can account for both premature and full term labour.
Year
DOI
Venue
2012
10.1007/978-3-642-28792-3_21
IPCAT
Keywords
Field
DocType
computational modelling,non-invasive clinical data,dysfunctional human labour,nonlinear wave process,full term labour,excitable medium,human uterine excitation pattern,experimental study,intercellular coupling parameter space,animal model,propagation phenomenon
Neuroscience,Synchronization,Excitable medium,Biology,Internal medicine,Excitation,Endocrinology
Conference
Citations 
PageRank 
References 
0
0.34
1
Authors
2
Name
Order
Citations
PageRank
Eleftheria Pervolaraki111.42
Arun V. Holden25220.71