Title
Practical implementation of a network-based stochastic biochemical simulation system on an FPGA
Abstract
Stochastic simulation of biochemical reaction networks are widely focused by life scientists to represent stochastic behaviors in cellular processes. Stochastic algorithm has loop-and thread-level parallelism, and it is suitable for running on application specific hardware to achieve high performance with low cost. We have implemented and evaluated the FPGA-based stochastic simulator according to theoretical research of the algorithm. This paper introduces an improved architecture for accelerating a stochastic simulation algorithm called the Next Reaction Method. This new architecture has scalability to various size of FPGA. As the result with a middle-range FPGA, 5.38 times higher throughput was obtained compared to software running on a Core 2 Quad Q6600 2.40 GHz.
Year
DOI
Venue
2008
10.1109/FPL.2008.4630034
Heidelberg
Keywords
Field
DocType
biochemistry,chemistry computing,field programmable gate arrays,stochastic processes,FPGA,network-based stochastic biochemical simulation system,next reaction method,stochastic algorithm
Stochastic simulation,Application specific,Simulation system,Computer science,Stochastic process,Field-programmable gate array,Real-time computing,Software,Throughput,Scalability
Conference
ISSN
ISBN
Citations 
1946-1488
978-1-4244-1961-6
2
PageRank 
References 
Authors
0.44
5
9
Name
Order
Citations
PageRank
Masato Yoshimi110622.49
Yuri Nishikawa2205.16
Yasunori Osana39218.24
Akira Funahashi426420.32
Yuichiro Shibata515737.99
Hideki Yamada6203.81
Noriko Hiroi17427.11
Hiroaki Kitano83515539.37
Hideharu Amano91375210.21