Title
Flexible, Efficient and Interactive Retrieval for Supporting In-silico Studies of Endobacteria
Abstract
Studying the interactions between arbuscular mycorrhizal fungi (AMFs) and their symbiotic endo bacteria has potentially strong impacts on the development of new biotechnology applications. The analysis of genomic data and syntenies is a key technique for acquiring information about phylogenetic relationships and metabolic functions of such organisms. In this paper we describe a case-based retrieval tool, which supports customized comparative genomics searches, and which is part of a modular architecture meant to support in-silico genome sequence analysis, being developed within the project BIOBITS. From a methodological viewpoint, the tool takes advantage of an abstraction technique similar to Temporal Abstractions, thus allowing to neglect un-relevant details. Retrieval is made flexible by the use of such multi-level abstractions, and efficient by the use of proper taxonomical index structures. Moreover, end-users are allowed to progressively relax or refine their queries, in an interactive way. A case study taken from the application domain is used to illustrate the approach.
Year
DOI
Venue
2011
10.1109/ICTAI.2011.12
ICTAI
Keywords
Field
DocType
in-silico studies,application domain,genomic data,temporal abstractions,arbuscular mycorrhizal fungus,comparative genomics search,case-based retrieval tool,key technique,case study,in-silico genome sequence analysis,interactive retrieval,abstraction technique,indexation,microorganisms,case base reasoning,indexes,comparative genomics,genome sequence,taxonomy,data analysis,genomics,bioinformatics,case based reasoning,biotechnology
Abstraction,Computer science,Comparative genomics,Genomics,Application domain,Artificial intelligence,Case-based reasoning,Machine learning,Modular architecture,Arbuscular mycorrhizal fungi,In silico
Conference
ISSN
ISBN
Citations 
1082-3409
978-1-4577-2068-0
0
PageRank 
References 
Authors
0.34
14
4
Name
Order
Citations
PageRank
Stefania Montani190181.42
Giorgio Leonardi217920.36
Stefano Ghignone301.35
Luisa Lanfranco401.35