Title
Local white matter geometry indices from diffusion tensor gradients.
Abstract
We introduce a framework for computing geometrical properties of white matter fibres directly from diffusion tensor fields. The key idea is to isolate the portion of the gradient of the tensor field corresponding to local variation in tensor orientation, and to project it onto a coordinate frame of tensor eigenvectors. The resulting eigenframe-centered representation makes it possible to define scalar geometrical measures that describe the underlying white matter fibres, directly from the diffusion tensor field and its gradient, without requiring prior tractography. We define two new scalar measures of (1) fibre dispersion and (2) fibre curving, and we demonstrate them on synthetic and in-vivo datasets. Finally, we illustrate their applicability in a group study on schizophrenia.
Year
DOI
Venue
2009
10.1007/978-3-642-04268-3_43
MICCAI
Keywords
Field
DocType
tensor orientation,scalar geometrical measure,diffusion tensor gradients,diffusion tensor field,fibre dispersion,new scalar measure,local white matter geometry,fibre curving,tensor eigenvectors,tensor field,geometrical property,underlying white matter fibre,diffusion tensor imaging,algorithms,eigenvectors,artificial intelligence,diffusion tensor
Diffusion MRI,Tensor,Fractional anisotropy,Scalar (physics),Tensor field,Structure tensor,Geometry,Tractography,Eigenvalues and eigenvectors,Mathematics
Conference
Volume
Issue
ISSN
12
Pt 1
0302-9743
Citations 
PageRank 
References 
0
0.34
3
Authors
5
Name
Order
Citations
PageRank
Peter Savadjiev114412.06
Gordon Kindlmann21598103.52
Sylvain Bouix387755.88
Martha E. Shenton439441.14
Carl-fredrik Westin52040173.83