Title
Distributed Systems and Automated Biodiversity Informatics: Genomic Analysis and Geographic Visualization of Disease Evolution
Abstract
A core mission in biodiversity informatics is to build a computing infrastructure for rapid, real-time analysis of biodiversity information. We have created the information technology to mine, analyze, interpret and visualize how diseases are evolving across the globe. The system rapidly collects the newest and most complete data on dangerous strains of viruses that are able to infect human and animal populations. Following completion, the system will also test whether positions in the genome are under positive selection or purifying selection, a useful feature to monitor functional genomic charac-teristics such as, drug resistance, host specificity, and transmissibility. Our system's persistent monitoring and reporting of the distribution of dangerous and novel viral strains will allow for better threat forecasting. This information system allows for greatly increased efficiency in tracking the evolution of disease threats.
Year
DOI
Venue
2008
10.1007/978-3-540-70504-8_28
BNCOD
Keywords
Field
DocType
animal population,positive selection,disease evolution,purifying selection,better threat forecasting,genomic analysis,dangerous strain,information technology,information system,complete data,biodiversity informatics,automated biodiversity informatics,geographic visualization,biodiversity information,functional genomics,distributed system,real time,drug resistance
Biodiversity,Data science,Genome,Information system,Geovisualization,Data mining,Negative selection,Biodiversity informatics,Viral evolution,Computer science,Information technology,Bioinformatics
Conference
Volume
ISSN
Citations 
5071
0302-9743
1
PageRank 
References 
Authors
0.36
4
2
Name
Order
Citations
PageRank
Andrew Hill1173.39
Robert Guralnick2315.63