Abstract | ||
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We report on a new algorithm for combining the information from several mass spectra of the same peptide. The algorithm automatically learns peptide fragmentation patterns, so that it can handle spectra from any instrument and fragmentation technique. We demonstrate the utility of the algorithm, and the power of multiple spectra, by showing that combining pairs of spectra (one CID and one ETD) greatly improves de novo sequencing success rates. |
Year | DOI | Venue |
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2009 | 10.1089/cmb.2009.0122 | Journal of computational biology : a journal of computational molecular cell biology |
Keywords | Field | DocType |
multiple mass spectrum,multiple spectrum,fragmentation technique,spectrum fusion,peptide fragmentation pattern,new algorithm,mass spectrum,novo sequencing success rate,spectrum,mass spectra | Peptide,Mass spectrum,Fusion,De novo peptide sequencing,Mass spectrometry,Bioinformatics,Mathematics | Journal |
Volume | Issue | ISSN |
16 | 8 | 1557-8666 |
ISBN | Citations | PageRank |
3-540-78838-7 | 8 | 0.71 |
References | Authors | |
8 | 2 |
Name | Order | Citations | PageRank |
---|---|---|---|
Ritendra Datta | 1 | 2526 | 104.69 |
Marshall W. Bern | 2 | 669 | 71.98 |