Title
Spectrum fusion: using multiple mass spectra for de novo Peptide sequencing.
Abstract
We report on a new algorithm for combining the information from several mass spectra of the same peptide. The algorithm automatically learns peptide fragmentation patterns, so that it can handle spectra from any instrument and fragmentation technique. We demonstrate the utility of the algorithm, and the power of multiple spectra, by showing that combining pairs of spectra (one CID and one ETD) greatly improves de novo sequencing success rates.
Year
DOI
Venue
2009
10.1089/cmb.2009.0122
Journal of computational biology : a journal of computational molecular cell biology
Keywords
Field
DocType
multiple mass spectrum,multiple spectrum,fragmentation technique,spectrum fusion,peptide fragmentation pattern,new algorithm,mass spectrum,novo sequencing success rate,spectrum,mass spectra
Peptide,Mass spectrum,Fusion,De novo peptide sequencing,Mass spectrometry,Bioinformatics,Mathematics
Journal
Volume
Issue
ISSN
16
8
1557-8666
ISBN
Citations 
PageRank 
3-540-78838-7
8
0.71
References 
Authors
8
2
Name
Order
Citations
PageRank
Ritendra Datta12526104.69
Marshall W. Bern266971.98