Title
Combined analysis of resting-state fMRI and DTI data reveals abnormal development of function-structure in early-onset schizophrenia
Abstract
A combined analysis by integrating the resting-state functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) is presented in this paper to investigate the structure-function relationship in early-onset schizophrenia. After fractional anisotropy in white matter was assessed, functional connectivity was analyzed with regions of reference which was defined according to the regions showed lower fractional anisotropy values. We found significant decreased functional connectivity in early-onset schizophrenia correlated with the regions of anisotropy changes. Our results demonstrated that the white matter lesions may disrupt the anatomical connectivity and inflect the functional connectivity between the frontal regions and other brain regions.
Year
DOI
Venue
2008
10.1007/978-3-540-79721-0_84
RSKT
Keywords
Field
DocType
functional connectivity,anatomical connectivity,white matter,resting-state functional magnetic resonance,combined analysis,anisotropy change,fractional anisotropy,abnormal development,diffusion tensor imaging,white matter lesion,resting-state fmri,early-onset schizophrenia,fractional anisotropy value,dti data,white matter lesions,resting state
Diffusion MRI,Anisotropy,Pattern recognition,Functional magnetic resonance imaging,White matter,Computer science,Fractional anisotropy,Resting state fMRI,Artificial intelligence,Nuclear magnetic resonance,Hyperintensity,Schizophrenia
Conference
Volume
ISSN
ISBN
5009
0302-9743
3-540-79720-3
Citations 
PageRank 
References 
3
0.57
5
Authors
6
Name
Order
Citations
PageRank
Ming Ke132.26
Xing Huang230.57
Hui Shen313415.32
Zongtan Zhou441233.89
Xiaogang Chen518425.18
Dewen Hu61290101.20