Abstract | ||
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Although many tools were developed for visualization of RNA secondary structure, RNA-DV is a tool which provides a flexible and powerful interface for RNA secondary structure design and visualization. Being able to dynamically make modification and visualize the result is the most significant contribution of RNA-DV. The ability to allow researcher to make edit and visualize the resulting structure help set apart RNA-DV from other existing tools. The structural modification is achieved through a combination of mouse and keyboard operations. The direct and intuitive interface allows the structure prediction researcher to visualize the structure. Furthermore, RNA-DV provides the necessary tool for structure designers to explore the effect of various structural elements in terms of thermodynamic contributions. Four different thermodynamic energy models (efn2, HotKnots, Major and RNAeval) were incorporated allowing users to observe real-time energy changes while designing the structure. Visualizing and editing of pseudo-knotted structure is also supported in RNA-DV. |
Year | DOI | Venue |
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2012 | 10.1145/2382936.2383036 | BCB |
Keywords | Field | DocType |
resulting structure help,rna secondary structure design,existing tool,pseudo-knotted structure,structure designer,rna secondary structure,necessary tool,structure prediction researcher,interactive tool,visualizing rna secondary structure,intuitive interface,different thermodynamic energy model,secondary structure,visualization,rna,bioinformatics | RNA,Thermodynamic free energy,Visualization,Computer science,Human–computer interaction,Protein secondary structure,Nucleic acid secondary structure | Conference |
Citations | PageRank | References |
1 | 0.35 | 7 |
Authors | ||
2 |
Name | Order | Citations | PageRank |
---|---|---|---|
Herbert H. Tsang | 1 | 92 | 19.08 |
Denny C. Dai | 2 | 6 | 1.18 |