Abstract | ||
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A DNA computation model by DNA tiles needs sequence design in order to correctly form tile structure and self-assembly. We design sequence, demonstrate biochemical experiments by a trial and error approach, and, repeatedly analyze tiles. Because no integrated sequence design system computes data that indicates properties of sequences, we must analyze designed sequences by hand and many types of software. In this paper, we develop a sequence design support system for 4 × 4 DNA tiles that analyzes and optimizes tile sequences to support sequence design. The most remarkable feature of this system is optimization based on free energy. The optimization strategy is developed so that the energy of perfect tile is the stablest. |
Year | DOI | Venue |
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2007 | 10.1007/978-3-540-77962-9_14 | DNA |
Keywords | Field | DocType |
dna tile,optimizes tile sequence,integrated sequence design system,dna computation model,optimization strategy,sequence design support system,free energy,tile structure,sequence design,perfect tile,dna computing,self assembly | Trial and error,Support system,Computer science,Algorithm,Sequence design,DNA,Software,Tile,A-DNA,Computation | Conference |
ISBN | Citations | PageRank |
3-540-77961-2 | 0 | 0.34 |
References | Authors | |
4 | 4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Naoki Iimura | 1 | 2 | 0.72 |
Masahito Yamamoto | 2 | 0 | 0.34 |
Fumiaki Tanaka | 3 | 40 | 5.96 |
Azuma Ohuchi | 4 | 386 | 68.99 |