Title
Sequence design support system for 4 × 4 DNA tiles
Abstract
A DNA computation model by DNA tiles needs sequence design in order to correctly form tile structure and self-assembly. We design sequence, demonstrate biochemical experiments by a trial and error approach, and, repeatedly analyze tiles. Because no integrated sequence design system computes data that indicates properties of sequences, we must analyze designed sequences by hand and many types of software. In this paper, we develop a sequence design support system for 4 × 4 DNA tiles that analyzes and optimizes tile sequences to support sequence design. The most remarkable feature of this system is optimization based on free energy. The optimization strategy is developed so that the energy of perfect tile is the stablest.
Year
DOI
Venue
2007
10.1007/978-3-540-77962-9_14
DNA
Keywords
Field
DocType
dna tile,optimizes tile sequence,integrated sequence design system,dna computation model,optimization strategy,sequence design support system,free energy,tile structure,sequence design,perfect tile,dna computing,self assembly
Trial and error,Support system,Computer science,Algorithm,Sequence design,DNA,Software,Tile,A-DNA,Computation
Conference
ISBN
Citations 
PageRank 
3-540-77961-2
0
0.34
References 
Authors
4
4
Name
Order
Citations
PageRank
Naoki Iimura120.72
Masahito Yamamoto200.34
Fumiaki Tanaka3405.96
Azuma Ohuchi438668.99