Title
DTI tractography based parcellation of white matter: application to the mid-sagittal morphology of corpus callosum.
Abstract
Morphology of the corpus callosum (CC) at the mid-sagittal level has been a target of extensive studies. However, the lack of internal structures and its polymorphism make it a challenging task to quantitatively analyze shape differences among subjects. In this paper, diffusion tensor Imaging (DTI) and tract tracing technique were applied to incorporate cortical connectivity information to the morphological study. The CC was parcellated into six major subdivisions based on trajectories to different cortical areas. This subdivision was performed for eight normal subjects and one stroke patient. The parcellated CCs of the normal subjects were normalized for morphological analysis. When comparing the stroke patient to the normal population, we detected significant atrophy in the motor and sensory areas of the patient CC, in line with the clinical deficits. This approach provides a new tool to investigate callosal morphology and functional relationships.
Year
DOI
Venue
2005
10.1016/j.neuroimage.2005.01.019
NeuroImage
Keywords
Field
DocType
DTI tractography,White matter,Tract,Parcellation,Inner landmark,Corpus callosum morphology,Stroke
Developmental psychology,Population,Neuroscience,Diffusion MRI,White matter,Psychology,Atrophy,Corpus callosum,Sagittal plane,Tractography,Morphological analysis
Journal
Volume
Issue
ISSN
26
1
1053-8119
Citations 
PageRank 
References 
38
5.20
5
Authors
10
Name
Order
Citations
PageRank
Hao Huang1589104.49
Jiangyang Zhang253738.34
Hangyi Jiang355031.16
Setsu Wakana419713.19
Lidia M Nagae5757.25
Michael I Miller63123422.82
Peter van Zijl7109073.41
Argye E. Hillis8679.87
Robert Wytik9385.20
Susumu Mori1064543.22