Title
Construction and assessment of a 3-T MRI brain template.
Abstract
New MR imaging protocols enable visualization of brain structures. However, for dedicated clinical applications such as targeting deep brain stimulation (DBS), a more accurate localization requires the use of atlases. We developed a three-dimensional digitized mono-subject anatomical template of the human brain based on 3-T magnetic resonance images (MRI). By averaging 15 registered T1 image acquisitions, we have shown that the final image corresponds to an optimal image, limited by the performance of the 3-T MR machine. We compared different preprocessing workflows for template construction. With the optimal strategy, along with validated existing processing methods, one T1 template and one T1–T2 mixing template were created in order to improve visualization of spatially complex deep structures. Reduction of voxel size to 0.25 mm3 was also advantageous to observe fine structures and white matter/gray matter intensity crossings. Results demonstrated that such a template also improved inter-patient registration for population comparison in DBS. These MR templates are made freely available to our community (http://www.vmip.org/mritemplate) to serve as a reference for neuroimage processing methods.
Year
DOI
Venue
2010
10.1016/j.neuroimage.2009.08.007
NeuroImage
Keywords
Field
DocType
Brain template,Basal ganglia,3-T MRI,Deep brain stimulation
Mr imaging,Voxel,Computer vision,Population,Visualization,Computer science,Preprocessor,Artificial intelligence,Template,Magnetic resonance imaging
Journal
Volume
Issue
ISSN
49
1
1053-8119
Citations 
PageRank 
References 
12
0.73
20
Authors
5
Name
Order
Citations
PageRank
Florent Lalys124816.44
Claire Haegelen211612.01
Jean-Christophe Ferre3120.73
Omar El-Ganaoui4120.73
Pierre Jannin564458.36