Title
Tunable magnetic alginate microspheres by using a microfluidic device
Abstract
This study presents a new method for generating tunable and uniform magnetic alginate microspheres, which can be widely employed in the field of the bead-based bio sample pretreatment and enrichment process during the clinical diagnoses. A microfluidic device comprising microchannels and controllable moving-wall structures was fabricated by using MEMS processes. The key feature of the controllable moving-wall structure is located nearby the flow-focusing microchannels and can be fine-tuned by the pneumatic pressure such that the sheath flows can be locally accelerated. With this approach, the size of the alginate microspheres can be fine-tuned without adjusting the syringe pumps. Therefore, the uniform magnetic alginate microspheres can be successfully generated.
Year
DOI
Venue
2010
10.1109/NEMS.2010.5592428
NEMS
Keywords
Field
DocType
flow-focusing microchannel,mems,bead-based bio sample pretreatment,microfluidic device,clinical diagnoses,pneumatic pressure,alginate,moving-wall structure,flow focusing,emulsification,microsphere,microfluidics,magnetic bead,magnetic materials,moving wall,tunable magnetic alginate microsphere,microchannel,nanoparticles,magnetic resonance imaging
Nanotechnology,Analytical chemistry,Microelectromechanical systems,Microfluidics,Flow focusing,Magnetic separation,Microchannel,Materials science,Microsphere,Nanoparticle,Magnetic liquids
Conference
ISBN
Citations 
PageRank 
978-1-4244-6543-9
0
0.34
References 
Authors
0
5
Name
Order
Citations
PageRank
Chen-Yi Lee11211152.40
Song-Bin Huang293.97
Kang-Yi Lien301.35
Ming-Yang Lin400.68
Gwo-Bin Lee5716.66