Title | ||
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Symmetric atlasing and model based segmentation: an application to the hippocampus in older adults. |
Abstract | ||
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In model-based segmentation, automated region identification is achieved via registration of novel data to a pre-determined model. The desired structure is typically generated via manual tracing within this model. When model-based segmentation is applied to human cortical data, problems arise if left-right comparisons are desired. The asymmetry of the human cortex requires that both left and right models of a structure be composed in order to effectively segment the desired structures. Paradoxically, defining a model in both hemi-spheres carries a likelihood of introducing bias to one of the structures. This paper describes a novel technique for creating a symmetric average model in which both hemispheres are equally represented and thus left-right comparison is possible. This work is an extension of that proposed by Guimond et al. Hippocampal segmentation is used as a test-case in a cohort of 118 normal eld-erly subjects and results are compared with expert manual tracing. |
Year | DOI | Venue |
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2006 | 10.1007/11866763_8 | MICCAI (2) |
Keywords | Field | DocType |
novel data,novel technique,hippocampal segmentation,model-based segmentation,pre-determined model,left-right comparison,right model,symmetric average model,human cortical data,human cortex,older adult,symmetric atlasing | Computer vision,Pattern recognition,Computer science,Segmentation,Artificial intelligence,Hippocampal formation,Tracing,Hippocampus | Conference |
Volume | Issue | ISSN |
9 | Pt 2 | 0302-9743 |
ISBN | Citations | PageRank |
3-540-44727-X | 41 | 2.66 |
References | Authors | |
4 | 6 |
Name | Order | Citations | PageRank |
---|---|---|---|
Günther Grabner | 1 | 60 | 4.93 |
Andrew L. Janke | 2 | 236 | 16.23 |
Marc M Budge | 3 | 41 | 2.66 |
David Smith | 4 | 41 | 2.66 |
Jens Pruessner | 5 | 60 | 3.86 |
D. Louis Collins | 6 | 3915 | 403.90 |