Title
Algorithms and complexity analyses for control of singleton attractors in Boolean networks.
Abstract
A Boolean network (BN) is a mathematical model of genetic networks. We propose several algorithms for control of singleton attractors in BN. We theoretically estimate the average-case time complexities of the proposed algorithms, and confirm them by computer experiments. The results suggest the importance of gene ordering. Especially, setting internal nodes ahead yields shorter computational time than setting external nodes ahead in various types of algorithms. We also present a heuristic algorithm which does not look for the optimal solution but for the solution whose computational time is shorter than that of the exact algorithms.
Year
DOI
Venue
2008
10.1155/2008/521407
EURASIP J. Bioinformatics and Systems Biology
Keywords
DocType
Volume
Internal Node, Boolean Network, Recursive Call, Average Computational Time, External Node
Journal
2008
Issue
ISSN
Citations 
1
1687-4145
6
PageRank 
References 
Authors
0.52
13
5
Name
Order
Citations
PageRank
Morihiro Hayashida115421.88
Takeyuki Tamura221023.66
Tatsuya Akutsu32169216.05
Shu-Qin Zhang41618.88
Wai-Ki Ching568378.66