Title
MRI characteristics of the substantia nigra in Parkinson's disease: A combined quantitative T1 and DTI study.
Abstract
The substantia nigra contains dopaminergic cells that project to the striatum and are affected by the neurodegenerative process that appears in Parkinson's disease (PD). For accurate differential diagnosis and for disease monitoring the availability of a sensitive and non-invasive biomarker for Parkinson's disease would be essential. Although there has been notable progress in studying correlates of nigral degeneration by means of magnetic resonance imaging (MRI) in the past decade, MRI and analysis techniques that allow accurate high-resolution mapping of the SN within a clinically acceptable acquisition time are still elusive.
Year
DOI
Venue
2009
10.1016/j.neuroimage.2009.05.017
NeuroImage
Keywords
Field
DocType
leave one out cross validation,discriminant function analysis,high resolution,magnetic resonance image
Developmental psychology,Diffusion MRI,Parkinson's disease,Striatum,Psychology,Biomarker (medicine),Substantia nigra,Discriminant function analysis,Differential diagnosis,Magnetic resonance imaging
Journal
Volume
Issue
ISSN
47
2
1053-8119
Citations 
PageRank 
References 
9
1.03
3
Authors
7
Name
Order
Citations
PageRank
Ricarda A Menke1775.50
Jan Scholz2596.29
Karla L. Miller3118058.71
Sean C. L. Deoni419016.12
Saad Jbabdi5123655.22
paul m matthews698977.13
mojtaba zarei7505.44