Title
Clinical decision-support for diagnosing stress-related disorders by applying psychophysiological medical knowledge to an instance-based learning system.
Abstract
An important procedure in diagnosing stress-related disorders caused by dysfunction in the interaction of the heart with breathing, i.e., respiratory sinus arrhythmia (RSA), is to analyse the breathing first and then the heart rate. Analysing these measurements is a time-consuming task for the diagnosing clinician. A decision-support system in this area would reduce the analysis task of the clinician and enable him/her to give more attention to the patient. We have created a decision-support system which contains a signal classifier and a pattern identifier. The system performs an analysis of the physiological time series concerned which would otherwise be performed manually by the clinician.The signal-classifier, HR3Modul, classifies heart-rate patterns by analysing both cardio- and pulmonary signals, i.e., physiological time series. HR3Modul uses case-based reasoning (CBR), using a wavelet-based method for retrieving features from the signals. The system searches for familiar shapes in the signals by comparing them with shapes already stored. We have applied a best fit scheme for handling signals of different lengths, as the length of a breath is highly dynamic. We also apply automatic weighting to the features to obtain a more autonomous system. The classified heart signals indicate if a patient may be suffering from a stress-related disorder and the nature of the disorder. These classified signals are thereafter sent to the second subsystem, the pattern-identifier. The pattern-identifier analyses the classified signals and searches for familiar patterns by identifying sequences in the classified signals. The identified sequences give clinicians a more complete analysis of the measurements, providing them with a better basis for diagnosis.We have shown that a case-based classifier with a wavelet feature extractor and automatic weighting is a viable option for building a decision-support system for the psychophysiological domain, as it is at par, or even outperforms other retrieval techniques and is less complex.
Year
DOI
Venue
2006
10.1016/j.artmed.2005.04.004
Artificial Intelligence In Medicine
Keywords
Field
DocType
complete analysis,classified signal,decision support,physiological time series,clinical decision-support,psychophysiological medical knowledge,autonomous system,automatic weighting,system search,stress-related disorder,respiratory sinus arrhythmia,instance-based learning system,analysis task,case-based classification,knowledge discovery,classified heart signal,decision-support system,wavelet retrieval,clinical decision support,instance based learning
Data mining,Weighting,Instance-based learning,Identifier,Computer science,Artificial intelligence,Knowledge extraction,Autonomous system (mathematics),Clinical decision support system,Classifier (linguistics),Machine learning,Wavelet
Journal
Volume
Issue
ISSN
36
2
0933-3657
Citations 
PageRank 
References 
28
1.03
16
Authors
5
Name
Order
Citations
PageRank
Markus Nilsson11005.52
P. Funk229122.99
Erik M G Olsson3281.37
Bo Von Schéele4693.14
Ning Xiong5281.03