Abstract | ||
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This paper presents a novel method integrating gene-gene interaction information and Gene Ontology (GO) for the construction of new gene sets that are potentially enriched. Enrichment of a gene set is determined by Gene Set Enrichment Analysis. The experimental results show that the introduced method improves over existing methods, i.e. that it is capable to find new descriptions of the biology governing the experiments, not detectable by the traditional methods of evaluating the enrichment of predefined gene sets, defined by a single GO term. |
Year | DOI | Venue |
---|---|---|
2007 | 10.1007/978-3-540-73599-1_16 | AIME '87 |
Keywords | Field | DocType |
traditional method,gene-gene interaction information,gene ontology,novel method,enriched gene sets,new description,interpreting gene expression data,gene set enrichment analysis,gene set,predefined gene set,new gene set,microarray data analysis,microarray data | Data mining,Gene,Gene ontology,Computer science,Gene expression,Chromosomal part,Microarray analysis techniques,Interaction information,Microarray databases,Gene expression profiling | Conference |
Volume | ISSN | Citations |
4594 | 0302-9743 | 1 |
PageRank | References | Authors |
0.35 | 5 | 2 |
Name | Order | Citations | PageRank |
---|---|---|---|
Igor Trajkovski | 1 | 54 | 5.84 |
Nada Lavrač | 2 | 989 | 72.19 |