Abstract | ||
---|---|---|
Multiple templates can often be used to build more accurate homology models than models built from a single template. Here we introduce PconsM, an automated protocol that uses multiple templates to build protein models. PconsM has been among the top-performing methods in the recent CASP experiments and consistently perform better than the single template models used in Pcons.net. In particular for the easier targets with many alternative templates with a high degree of sequence identity, quality is readily improved with a few percentages over the highest ranked model built on a single template. PconsM is available as an additional pipeline within the Pcons.net protein structure prediction server.PconsM is freely available from http://pcons.net/. |
Year | DOI | Venue |
---|---|---|
2011 | 10.1093/bioinformatics/btq664 | Bioinformatics |
Keywords | DocType | Volume |
alternative template,multiple template,accurate homology model,easier target,improved prediction,single template,automated protocol,protein structure prediction server,protein model,single template model,additional pipeline,computational biology,proteins | Journal | 27 |
Issue | ISSN | Citations |
3 | 1367-4811 | 4 |
PageRank | References | Authors |
0.45 | 1 | 4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Per Larsson | 1 | 82 | 5.76 |
Marcin J. Skwark | 2 | 144 | 8.76 |
Björn Wallner | 3 | 93 | 9.07 |
Arne Elofsson | 4 | 633 | 56.98 |