Title
Improved predictions by Pcons.net using multiple templates.
Abstract
Multiple templates can often be used to build more accurate homology models than models built from a single template. Here we introduce PconsM, an automated protocol that uses multiple templates to build protein models. PconsM has been among the top-performing methods in the recent CASP experiments and consistently perform better than the single template models used in Pcons.net. In particular for the easier targets with many alternative templates with a high degree of sequence identity, quality is readily improved with a few percentages over the highest ranked model built on a single template. PconsM is available as an additional pipeline within the Pcons.net protein structure prediction server.PconsM is freely available from http://pcons.net/.
Year
DOI
Venue
2011
10.1093/bioinformatics/btq664
Bioinformatics
Keywords
DocType
Volume
alternative template,multiple template,accurate homology model,easier target,improved prediction,single template,automated protocol,protein structure prediction server,protein model,single template model,additional pipeline,computational biology,proteins
Journal
27
Issue
ISSN
Citations 
3
1367-4811
4
PageRank 
References 
Authors
0.45
1
4
Name
Order
Citations
PageRank
Per Larsson1825.76
Marcin J. Skwark21448.76
Björn Wallner3939.07
Arne Elofsson463356.98