Title
Inferring Neural Firing Rates from Spike Trains Using Gaussian Processes
Abstract
Neural spike trains present challenges to analytical efforts due to their noisy, spiking nature. Many studies of neuroscientic and neural prosthetic importance rely on a smoothed, denoised estimate of the spike train's underlying ring rate. Current techniques to nd time-varying ring rates require ad hoc choices of parameters, offer no condence intervals on their estimates, and can obscure potentially important single trial variability. We present a new method, based on a Gaussian Process prior, for inferring probabilistically optimal estimates of ring rate functions underlying single or multiple neural spike trains. We test the performance of the method on simulated data and experimentally gathered neural spike trains, and we demonstrate improvements over conventional estimators.
Year
Venue
Keywords
2007
NIPS
optimal estimation,gaussian process
Field
DocType
Citations 
Spike train,Computer science,Gaussian process,Artificial intelligence,Train,Machine learning,Estimator
Conference
26
PageRank 
References 
Authors
2.62
3
4
Name
Order
Citations
PageRank
John P. Cunningham128834.41
Byron M. Yu211513.65
Krishna V. Shenoy330260.98
Maneesh Sahani444150.70