Name
Abstract | ||
|---|---|---|
SITEHOUND-web (http://sitehound.sanchezlab.org) is a binding-site identification server powered by the SITEHOUND program. Given a protein structure in PDB format SITEHOUND-web will identify regions of the protein characterized by favorable interactions with a probe molecule. These regions correspond to putative ligand binding sites. Depending on the probe used in the calculation, sites with preference for different ligands will be identified. Currently, a carbon probe for identification of binding sites for drug-like molecules, and a phosphate probe for phosphorylated ligands (ATP, phoshopeptides, etc.)have been implemented. SITEHOUND web will display the results in HTML pages including an interactive 3D representation of the protein structure and the putative sites using the Jmol java applet. Various downloadable data files are also provided for offline data analysis. |
Year | DOI | Venue |
|---|---|---|
2009 | 10.1093/nar/gkp281 | NUCLEIC ACIDS RESEARCH |
Keywords | Field | DocType |
algorithms,data analysis,internet,protein conformation,ligand binding,binding site,ligands,binding sites,protein structure,java applet | Binding site,Biology,Ligand,Ligand (biochemistry),Interactive 3d,Java applet,Computational biology,Bioinformatics,Genetics,Protein Data Bank (RCSB PDB),Protein structure | Journal |
Volume | Issue | ISSN |
37 | Web Server issue | 0305-1048 |
Citations | PageRank | References |
30 | 1.64 | 5 |
Authors | ||
3 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Marylens Hernandez | 1 | 30 | 1.98 |
| Dario Ghersi | 2 | 66 | 7.04 |
| Roberto Sanchez | 3 | 50 | 4.68 |