Paper Info
Title
Dragon Gene Start Finder identifies approximate locations of the 5' ends of genes.
Abstract
Recognition of gene starts is a difficult and yet unsolved problem. We present a program, Dragon Gene Start Finder (DGSF), which assesses the gene start in mammalian genomes and predicts a region which should overlap with the first exon of the gene or be in its proximity. The program has been rigorously tested on human chromosomes 4, 21 and 22, and in a strand specific search achieves an overall sensitivity of similar to65% and a positive predictive value of similar to78%. The sensitivity for the CpG-island related promoters is >88%. DGSF is free for academic and non-profit users at http://sdmc.lit.org.sg/promoter/dragonGSF1_0/genestart.htm; the download version of the program integrated within the TRANSPLORER(TM) package can be obtained from Biobase GmbH, at http://www.biobase.de/.
Year
DOI
Venue
2003
10.1093/nar/gkg570
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
5 flanking region,cpg island,algorithms,profitability,cpg islands,internet
Genome,Promoter,Gene,Biology,5' flanking region,Exon,Genetics
Journal
Volume
Issue
ISSN
31
13
0305-1048
Citations 
PageRank 
References 
8
0.63
8
Authors
2
Name
Order
Citations
PageRank
Vladimir B. Bajic132133.71
S H Seah27910.51