Title
T Cell Receptor Signalling Inspired Kernel Density Estimation and Anomaly Detection
Abstract
The T cell is able to perform fine-grained anomaly detection via its T Cell Receptor and intracellular signalling networks. We abstract from models of T Cell signalling to develop a new Artificial Immune System concepts involving the internal components of the TCR. We show that the concepts of receptor signalling have a natural interpretation as Parzen Window Kernel Density Estimation applied to anomaly detection. We then demonstrate how the dynamic nature of the receptors allows anomaly detection when probability distributions vary in time.
Year
DOI
Venue
2009
10.1007/978-3-642-03246-2_15
ICARIS
Keywords
Field
DocType
artificial immune system,anomaly detection,t cell receptor,probability distribution,kernel density estimate,cell signalling
T-cell receptor,Anomaly detection,Artificial immune system,Signalling,Computer science,Receptor,Probability distribution,Artificial intelligence,T cell,Machine learning,Kernel density estimation
Conference
Volume
ISSN
Citations 
5666
0302-9743
12
PageRank 
References 
Authors
0.92
4
4
Name
Order
Citations
PageRank
Nick D. L. Owens11169.18
Andrew J. Greensted2777.39
Jon Timmis31237120.32
Andrew M. Tyrrell432649.07