Title
Massive Multiple Sequence Alignment of 16S Bacterial Ribosomal RNAs Using ClustalW-Message Passing Interface (MPI) Based on Beowulf Linux System
Abstract
We have built a Debian-Beowulf computer cluster consisting of 15 computational nodes, each equipped with 15 AMD Opteron 64 bit microprocessors. Local Area Multicomputer (LAM)Message Passing Interface (MPI) was used as a portable highperformance implementation for MPI. More than 2,000 bacterial 16S ribosomal RNAs (rRNAs) were multiply aligned using ClustalW-MPI. Systematic sequence comparison provided several sequences with a very high degree of homology despite their different origins of species. These highly conservative sequences were collected as candidate sequences for drug targets of ribosomal antibiotics.
Year
DOI
Venue
2005
10.1109/CSBW.2005.88
CSB Workshops
Keywords
Field
DocType
amd opteron,candidate sequence,bacterial ribosomal,computational node,ribosomal antibiotic,beowulf linux system,massive multiple sequence alignment,conservative sequence,debian-beowulf computer cluster,ribosomal rnas,bit microprocessors,message passing interface,local area multicomputer,clustalw-message passing interface,drug targeting,linux,macromolecules,message passing,16s ribosomal rna,ribosomal rna,microorganisms,multiple sequence alignment
Cellular biophysics,Computer science,Ribosomal RNA,Message Passing Interface,Bioinformatics,Multiple sequence alignment,Bacterial 16S,Computer cluster,Message passing
Conference
ISBN
Citations 
PageRank 
0-7695-2442-7
0
0.34
References 
Authors
2
6
Name
Order
Citations
PageRank
Hyon Chang Kim100.34
Yong Beom Seo200.34
Ji Hwan Song300.34
Dong Soon Choi410.77
Churl K. Min500.34
Han Jip Kim600.34