Title
A novel clinical expert system for chest pain risk assessment
Abstract
Rapid access chest pain clinics (RACPC) enable clinical risk assessment, investigation and arrangement of a treatment plan for chest pain patients without a long waiting list. RACPC Clinicians often experience difficulties in the diagnosis of chest pain due to the inherent complexity of the clinical process and lack of comprehensive automated diagnostic tools. To date, various risk assessment models have been proposed, inspired by the National Institute of Clinical Excellence (NICE) guidelines to provide clinical decision support mechanism in chest pain diagnosis. The aim of this study is to help improve the performance of RACPC, specifically from the clinical decision support perspective. The study cohort comprises of 632 patients suspected of cardiac chest pain. A retrospective data analysis of the clinical studies evaluating 14 risk factors for chest pain patients was performed for the development of RACPC specific risk assessment models to distinguish between cardiac and non cardiac chest pain. In the first phase, a novel binary classification model was developed using a Decision Tree algorithm in conjunction with forward and backward selection wrapping techniques. Secondly, a logistic regression model was trained using all of the given variables combined with forward and backward feature selection techniques to identify the most significant features. The new models have resulted in very good predictive power, demonstrating general performance improvement compared to a state-of-the-art prediction model.
Year
DOI
Venue
2013
10.1007/978-3-642-38786-9_34
BICS
Keywords
Field
DocType
cardiac chest pain,chest pain risk assessment,clinical risk assessment,rapid access chest pain,clinical decision support perspective,chest pain diagnosis,chest pain patient,clinical process,chest pain,clinical decision support mechanism,novel clinical expert system,non cardiac chest pain
Physical therapy,Nice,Risk assessment,Chest pain,Clinical decision support system,Logistic regression,Specific risk,Medicine,Cohort,Decision tree learning
Conference
Citations 
PageRank 
References 
3
0.51
3
Authors
7
Name
Order
Citations
PageRank
Kamran Farooq1122.63
Amir Hussain267267.84
Hicham Atassi3231.95
Stephen J. Leslie4325.29
Chris Eckl518211.27
Calum MacRae691.54
Warner V. Slack74610.38