Title | ||
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3dLOGO: a web server for the identification, analysis and use of conserved protein substructures. |
Abstract | ||
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3dLOGO is a web server for the identification and analysis of conserved protein 3D substructures. Given a set of residues in a PDB (Protein Data Bank) chain, the server detects the matching substructure(s) in a set of user-provided protein structures, generates a multiple structure alignment centered on the input substructures and highlights other residues whose structural conservation becomes evident after the defined superposition. Conserved residues are proposed to the user for highlighting functional areas, deriving refined structural motifs or building sequence patterns. Residue structural conservation can be visualized through an expressly designed Java application, 3dProLogo, which is a 3D implementation of a sequence logo. The 3dLOGO server, with related documentation, is available at http://3dlogo.uniroma2.it/. |
Year | DOI | Venue |
---|---|---|
2007 | 10.1093/nar/gkm228 | NUCLEIC ACIDS RESEARCH |
Keywords | Field | DocType |
protein conformation,computer graphics,protein structure,computational biology,structure alignment,algorithms,protein data bank,internet,sequence alignment,conserved sequence,amino acid sequence,programming languages | Sequence alignment,Sequence logo,Conserved sequence,Structural alignment,Biology,Theoretical computer science,Bioinformatics,Protein Data Bank,Genetics,Protein Data Bank (RCSB PDB),Web server,Protein structure | Journal |
Volume | Issue | ISSN |
35 | SUPnan | 0305-1048 |
Citations | PageRank | References |
2 | 0.39 | 11 |
Authors | ||
7 |
Name | Order | Citations | PageRank |
---|---|---|---|
Allegra Via | 1 | 616 | 44.62 |
Daniele Peluso | 2 | 475 | 22.09 |
Pier Federico Gherardini | 3 | 102 | 5.21 |
Emanuele de Rinaldis | 4 | 29 | 1.10 |
Teresa Colombo | 5 | 18 | 1.92 |
Gabriele Ausiello | 6 | 301 | 23.59 |
Manuela Helmer-Citterich | 7 | 456 | 33.41 |