Title
Ymf: A Program For Discovery Of Novel Transcription Factor Binding Sites By Statistical Overrepresentation
Abstract
A fundamental challenge facing biologists is to identify DNA binding sites for unknown regulatory factors, given a collection of genes believed to be coregulated. The program YMF identifies good candidates for such binding sites by searching for statistically overrepresented motifs. More specifically, YMF enumerates all motifs in the search space and is guaranteed to produce those motifs with greatest z-scores. This note describes the YMF web software, available at http://bio.cs.washington.edu/software.html.
Year
DOI
Venue
2003
10.1093/nar/gkg618
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
description,local search,gene family,search space,gibbs sampling,global optimization,algorithms,binding sites,expectation maximization,transcription factors,binding site,standard deviation,internet,transcription factor,transcription factor binding site
Gene,Binding site,Biology,DNA binding site,DNA,Saccharomyces cerevisiae,Genetics,Molecular biology,Transcription factor
Journal
Volume
Issue
ISSN
31
13
0305-1048
Citations 
PageRank 
References 
98
5.24
5
Authors
2
Name
Order
Citations
PageRank
Saurabh Sinha152948.96
Martin Tompa21103149.69