Title
High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding.
Abstract
Mood disorders are elicited through a combination of genetic and environmental stress factors, and treatment with selective serotonin reuptake inhibitors ameliorates depressive symptoms. Changes in the serotonin transporter (SERT) binding may therefore occur in depressive patients and in subjects at risk for developing depression. The aim of this study was to explore whether abnormalities in SERT might be present in healthy individuals with familial predisposition to mood disorder.
Year
DOI
Venue
2009
10.1016/j.neuroimage.2009.02.008
NeuroImage
Keywords
Field
DocType
Serotonin,5-HT,5-HTT,PET,Depression,Imaging
Developmental psychology,Mood,Mood disorders,DASB,Dorsolateral prefrontal cortex,Psychology,Orbitofrontal cortex,Serotonin transporter,Reuptake inhibitor,Ventrolateral prefrontal cortex
Journal
Volume
Issue
ISSN
46
2
1053-8119
Citations 
PageRank 
References 
2
0.43
1
Authors
10