Title
Monitoring motor fluctuations in patients with Parkinson's disease using wearable sensors.
Abstract
This paper presents the results of a pilot study to assess the feasibility of using accelerometer data to estimate the severity of symptoms and motor complications in patients with Parkinson's disease. A support vector machine (SVM) classifier was implemented to estimate the severity of tremor, bradykinesia and dyskinesia from accelerometer data features. SVM-based estimates were compared with clinical scores derived via visual inspection of video recordings taken while patients performed a series of standardized motor tasks. The analysis of the video recordings was performed by clinicians trained in the use of scales for the assessment of the severity of Parkinsonian symptoms and motor complications. Results derived from the accelerometer time series were analyzed to assess the effect on the estimation of clinical scores of the duration of the window utilized to derive segments (to eventually compute data features) from the accelerometer data, the use of different SVM kernels and misclassification cost values, and the use of data features derived from different motor tasks. Results were also analyzed to assess which combinations of data features carried enough information to reliably assess the severity of symptoms and motor complications. Combinations of data features were compared taking into consideration the computational cost associated with estimating each data feature on the nodes of a body sensor network and the effect of using such data features on the reliability of SVM-based estimates of the severity of Parkinsonian symptoms and motor complications.
Year
DOI
Venue
2009
10.1109/TITB.2009.2033471
IEEE Transactions on Information Technology in Biomedicine
Keywords
Field
DocType
wearable sensor,monitoring motor fluctuation,different motor task,parkinsonian symptom,svm-based estimate,video recording,data feature,clinical score,accelerometer data,accelerometer data feature,motor complication,standardized motor task,support vector machines,accelerometers,neurophysiology,feature extraction,visual inspection,fluctuations,indexing terms,time series,patient monitoring,support vector machine,inspection
Visual inspection,Computer science,Remote patient monitoring,Artificial intelligence,Physical medicine and rehabilitation,Classifier (linguistics),Severity of illness,Computer vision,Neurophysiology,Accelerometer,Support vector machine,Feature extraction,Speech recognition
Journal
Volume
Issue
ISSN
13
6
1558-0032
Citations 
PageRank 
References 
141
13.02
2
Authors
10
Search Limit
100141
Name
Order
Citations
PageRank
Shyamal Patel140442.72
Konrad Lorincz22030136.77
Richard Hughes318024.69
Nancy Huggins416221.43
John Growdon514313.45
David Standaert616421.93
Metin Akay728850.47
Jennifer G. Dy81567126.18
Matt Welsh97657599.18
p bonato1028239.26