Title
Statistical image reconstruction for hybrid fluorescence optical tomography and positron emission tomography
Abstract
We have developed a hybrid system for imaging small animals using fluorescence optical tomography (FOT) and positron emission tomography (PET) simultaneously. This paper presents a statistical method for reconstructing spatial distribution of dual-labeled tracers from the combined PET and FOT data. We use the Poisson likelihood function for the PET data and Gaussian distribution for the FOT data. The log-posterior density function is maximized by an optimization transfer algorithm. Computer simulations show that the hybrid reconstruction using combined PET-FOT data can achieve a better bias versus standard deviation performance than reconstructions using either PET or FOT data alone.
Year
DOI
Venue
2011
10.1109/ISBI.2011.5872451
ISBI
Keywords
Field
DocType
optimisation,optical tomography,poisson distribution,dual-labeled tracers,biomedical optical imaging,optimization transfer algorithm,log-posterior density function,statistical analysis,hybrid system,gaussian distribution,fluorescence,pet,image reconstruction,statistical image reconstruction,fluorescence optical tomography,positron emission tomography,poisson likelihood function,medical image processing,fot,standard deviation,computer simulation,optical imaging,likelihood function
Nuclear medicine,Artificial intelligence,Positron emission tomography,Optical tomography,Iterative reconstruction,Likelihood function,Pattern recognition,Optics,Gaussian,Hybrid system,Probability density function,Standard deviation,Physics
Conference
ISSN
ISBN
Citations 
1945-7928 E-ISBN : 978-1-4244-4128-0
978-1-4244-4128-0
1
PageRank 
References 
Authors
0.41
0
4
Name
Order
Citations
PageRank
Guobao Wang18612.68
Changqing Li212.10
Simon R. Cherry363.17
Jinyi Qi428435.82