Title
Optimization Of Mri Protocols And Pulse Sequence Parameters For Eigenimage Filtering
Abstract
The eigenimage filter generates a composite image in which a desired feature is segmented from interfering features. The signal-to-noise ratio (SNR) of the eigenimage equals its contrast-to-noise ratio (CNR) and is directly proportional to the dissimilarity between the desired and interfering features. Since image gray levels are analytical functions of magnetic resonance imaging (MRI) parameters, it is possible to maximize this dissimilarity by optimizing these parameters. For optimization, we consider four MRI pulse sequences: multiple spin-echo (MSE); spin-echo (SE); inversion recovery (IR); and gradient-echo (GE). We use the mathematical expressions for MRI signals along with intrinsic tissue parameters to express the objective function (normalized SNR of the eigenimage) in terms of MRI parameters. The objective function along with a set of diagnostic or instrumental constraints define a multidimensional nonlinear constrained optimization problem, which we solve by the fixed point approach. The optimization technique is demonstrated through its application to phantom and brain images. We show that the optimal pulse sequence parameters for a sequence of four MSE and one IR images almost doubles the smallest normalized SNR of the brain eigenimages, as compared to the conventional brain protocol.
Year
DOI
Venue
1994
10.1109/42.276155
IEEE TRANSACTIONS ON MEDICAL IMAGING
Keywords
Field
DocType
spin echo,objective function,contrast to noise ratio,composite image,fixed point,analytical functions,brain imaging,image segmentation,magnetic resonance imaging,protocols,magnetic resonance image,analytic function,image analysis,signal to noise ratio
Normalization (statistics),Expression (mathematics),Analytic function,Imaging phantom,Artificial intelligence,Fixed point,Computer vision,Pulse sequence,Filter (signal processing),Algorithm,Composite image filter,Nuclear magnetic resonance,Mathematics
Journal
Volume
Issue
ISSN
13
1
0278-0062
Citations 
PageRank 
References 
10
1.06
2
Authors
5
Name
Order
Citations
PageRank
Hamid Soltanian-Zadeh124422.92
R Saigal2101.06
J P Windham3395.80
A. E. Yagle49524.97
David O Hearshen5142.20