Paper Info
Title
Magnetoencephalographic evidence for the modulation of cortical swallowing processing by transcranial direct current stimulation.
Abstract
Swallowing is a complex neuromuscular task that is processed within multiple regions of the human brain. Rehabilitative treatment options for dysphagia due to neurological diseases are limited. Because the potential for adaptive cortical changes in compensation of disturbed swallowing is recognized, neuromodulation techniques like transcranial direct current stimulation (tDCS) are currently considered as a treatment option. Here we evaluate the effect of tDCS on cortical swallowing network activity and behavior. In a double-blind crossover study, anodal tDCS (20min, 1mA) or sham stimulation was administered over the left or right swallowing motor cortex in 21 healthy subjects in separate sessions. Cortical activation was measured using magnetoencephalography (MEG) before and after tDCS during cued “simple”, “fast” and “challenged” swallow tasks with increasing levels of difficulty. Swallowing response times and accuracy were measured. Significant bilateral enhancement of cortical swallowing network activation was found in the theta frequency range after left tDCS in the fast swallow task (p=0.006) and following right tDCS in the challenged swallow task (p=0.007), but not after sham stimulation. No relevant behavioral effects were observed on swallow response time, but swallow precision improved after left tDCS (p<0.05).
Year
DOI
Venue
2013
10.1016/j.neuroimage.2013.06.055
NeuroImage
Keywords
DocType
Volume
Transcranial direct current stimulation,Magnetoencephalography,Swallowing,Deglutition,Swallowing disorders,Neuroplasticity
Journal
83
ISSN
Citations 
PageRank 
1053-8119
2
0.42
References 
Authors
6
8
Name
Order
Citations
PageRank
Sonja Suntrup120.76
Inga Teismann220.42
Andreas Wollbrink3345.33
Martin Winkels420.42
Tobias Warnecke520.76
Agnes Flöel6517.91
Christo Pantev79013.71
Rainer Dziewas820.76