Title
Evolutionary symbolic discovery for bioinformatics, systems and synthetic biology
Abstract
Symbolic regression and modeling are tightly linked in many Bioinformatics, Systems and Synthetic Biology problems. In this paper we briefly overview two problems, and the approaches we have use to tackle them, that can be deemed to represent this entwining of regression and modeling, namely, the evolutionary discovery of (1) effective energy functions for protein structure prediction and (2) models that capture biological behavior at the gene, signaling and metabolic networks level. These problems are not, strictly speaking, "regression problems" but they do share several characteristics with the latter, namely, a symbolic representation of a solution is sought, this symbolic representation must be human understandable and the results obtained by the symbolic and human interpretable solution must fit the available data without over-learning.
Year
DOI
Venue
2010
10.1145/1830761.1830842
GECCO (Companion)
Keywords
DocType
Citations 
available data,symbolic representation,synthetic biology,human interpretable solution,regression problem,evolutionary symbolic discovery,biological behavior,effective energy function,synthetic biology problem,symbolic regression,metabolic networks level,evolutionary discovery,protein structure,genetics,systems biology,data mining,system biology,protein structure prediction,modeling,metabolic network,p system
Conference
0
PageRank 
References 
Authors
0.34
25
5
Name
Order
Citations
PageRank
Pawel Widera1393.78
Jaume Bacardit2109147.21
Natalio Krasnogor3121385.53
Carlos GarcíA-MartíNez452027.80
Manuel Lozano5273.81