Title
A clinical outcome evaluation model with local sample selection: A study on efficacy of acupuncture for cervical spondylosis
Abstract
Local learning is a special learning framework that considers training samples located in a small region concentric of the query sample. In many applications the concept label of query sample can be evaluated effectively only by similar training samples, such as the famous K-nearest neighbors (KNN) classifier. The metric of locality or similarity is essential in local learning, which is often application oriented and implied in local geometry of input space. In this paper, we propose to apply local learning to the task of outcome assessment and evaluation on acupuncture for cervical spondylosis (CS) in a multi-center clinical trial. The analytic data are measures of three questionnaires which are recognized tools for subjective patient-reported outcomes (PROs) evaluation. We propose a similarity evaluation method based on both Euclidean distance and the therapy effect of recent records. A Non-Dominated Sort (NDS) based methods is applied to obtain a ranking of therapy effect. A WEKA implementation decision tree classifier is applied as the main learner in our work, with comparison to two base line methods. The result shows that the proposed local learning method dramatically outperforms the global version in both classification accuracy and computational costs.
Year
DOI
Venue
2011
10.1109/BIBMW.2011.6112480
BIBM Workshops
Keywords
Field
DocType
local sample selection,special learning framework,clinical outcome evaluation model,query sample,base line method,local learning,similarity evaluation method,similar training sample,proposed local learning method,euclidean distance,cervical spondylosis,local geometry,therapy effect,support vector machine,acupuncture,decision tree classifier,decision trees,k nearest neighbor,clinical trial,data mining
Data mining,Decision tree,Locality,Ranking,Computer science,Euclidean distance,Support vector machine,sort,Artificial intelligence,Classifier (linguistics),Machine learning,Decision tree learning
Conference
ISSN
Citations 
PageRank 
2163-6966
0
0.34
References 
Authors
4
7
Name
Order
Citations
PageRank
Zhong Di101.01
Hong-Lai Zhang222.76
Gang Zhang300.34
Zhaohui Liang42615.31
Li Jiang500.34
Jian-Hua Liu600.34
Wenbin Fu799.14