Title
New computational methods for the construction of "darcyan" biological coordinate systems
Abstract
In this paper we pursue the goal of constructing a biologically meaningful coordinate system that (i) carries information about the spatial distribution of gene activity regions and (ii) captures its effect on the internal structure and shape of an organism during its growth. Geometrically, this "Darcyan" coordinate system is curvilinear and comprised of an interior grid surrounded by a closed curve, namely the boundary of the organism. We explore two computational methods of constructing it, one based on potential theory (Poisson equation) and the other based on level set methods, with particular emphasis placed on the latter. We propose a novel algorithm that uses image processing tools for the extraction of the boundary, from which is produced the interior Darcyan coordinate system by means of level set evolution. Examples show the ability of the proposed algorithm to handle the complex geometry of the initial boundary such as significant oscillations, corners and cusps.
Year
DOI
Venue
2007
10.1007/978-3-540-74260-9_13
ICIAR
Keywords
Field
DocType
initial boundary,computational method,level set method,poisson equation,novel algorithm,interior grid,new computational method,proposed algorithm,complex geometry,level set evolution,closed curve,image processing,coordinate system,level set,potential theory,oscillations
Coordinate system,Topology,Poisson's equation,Ellipsoidal coordinates,Computer science,Level set,Coordinate space,Complex geometry,Curvilinear coordinates,Grid
Conference
Volume
ISSN
ISBN
4633
0302-9743
3-540-74258-1
Citations 
PageRank 
References 
1
0.38
1
Authors
3
Name
Order
Citations
PageRank
N. Portman131.44
Ulf Grenander230880.59
Edward R. Vrscay323525.15