Title | ||
---|---|---|
Cognitive state and connectivity effects of the genome-wide significant psychosis variant in ZNF804A. |
Abstract | ||
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Alterations of connectivity are central to the systems-level pathophysiology of schizophrenia. One of the best-established genome-wide significant risk variants for this highly heritable disorder, the rs1344706 single nucleotide polymorphism in ZNF804A, was recently shown to modulate connectivity in healthy carriers during working memory (WM) in a pattern mirroring that which was found in overt disease. However, it was unclear whether this finding is specific to WM or if it is present regardless of cognitive state. Therefore, we examined genotype effects on connectivity in healthy carriers during rest and an emotion processing task without WM component. |
Year | DOI | Venue |
---|---|---|
2011 | 10.1016/j.neuroimage.2010.10.012 | NeuroImage |
Keywords | Field | DocType |
working memory,single nucleotide polymorphism,functional imaging,genetics | Voxel,Developmental psychology,Allele,Psychosis,Working memory,Psychology,Functional imaging,Single-nucleotide polymorphism,Cognition,Schizophrenia | Journal |
Volume | Issue | ISSN |
54 | 3 | 1053-8119 |
Citations | PageRank | References |
10 | 0.92 | 9 |
Authors | ||
13 |
Name | Order | Citations | PageRank |
---|---|---|---|
Christine Esslinger | 1 | 110 | 5.45 |
P Kirsch | 2 | 115 | 7.55 |
Leila Haddad | 3 | 110 | 5.45 |
Daniela Mier | 4 | 110 | 5.92 |
Carina Sauer | 5 | 95 | 4.41 |
Susanne Erk | 6 | 125 | 9.64 |
Knut Schnell | 7 | 23 | 2.11 |
Claudia Arnold | 8 | 10 | 0.92 |
Stephanie H Witt | 9 | 12 | 2.47 |
Marcella Rietschel | 10 | 27 | 5.81 |
Sven Cichon | 11 | 12 | 1.64 |
Henrik Walter | 12 | 198 | 25.70 |
Andreas Meyer-Lindenberg | 13 | 253 | 18.54 |