Title
Data-driven breast decompression and lesion mapping from digital breast tomosynthesis.
Abstract
Digital breast tomosynthesis (DBT) emerges as a new 3D modality for breast cancer screening and diagnosis. Like in conventional 2D mammography the breast is scanned in a compressed state. For orientation during surgical planning, e.g., during presurgical ultrasound-guided anchor-wire marking, as well as for improving communication between radiologists and surgeons it is desirable to estimate an uncompressed model of the acquired breast along with a spatial mapping that allows localizing lesions marked in DBT in the uncompressed model. We therefore propose a method for 3D breast decompression and associated lesion mapping from 3D DBT data. The method is entirely data-driven and employs machine learning methods to predict the shape of the uncompressed breast from a DBT input volume. For this purpose a shape space has been constructed from manually annotated uncompressed breast surfaces and shape parameters are predicted by multiple multi-variate Random Forest regression. By exploiting point correspondences between the compressed and uncompressed breasts, lesions identified in DBT can be mapped to approximately corresponding locations in the uncompressed breast model. To this end, a thin-plate spline mapping is employed. Our method features a novel completely data-driven approach to breast shape prediction that does not necessitate prior knowledge about biomechanical properties and parameters of the breast tissue. Instead, a particular deformation behavior (decompression) is learned from annotated shape pairs, compressed and uncompressed, which are obtained from DBT and magnetic resonance image volumes, respectively. On average, shape prediction takes 26s and achieves a surface distance of 15.80 +/- 4.70 mm. The mean localization error for lesion mapping is 22.48 +/- 8.67 mm.
Year
DOI
Venue
2012
10.1007/978-3-642-33415-3_54
MICCAI
Keywords
Field
DocType
breast shape prediction,breast cancer screening,data-driven breast decompression,breast decompression,uncompressed model,breast tissue,lesion mapping,uncompressed breast surface,uncompressed breast,digital breast tomosynthesis,acquired breast,uncompressed breast model
Spline (mathematics),Mammography,Computer vision,Surgical planning,Data-driven,Decompression,Pattern recognition,Computer science,Breast cancer screening,Artificial intelligence,Random forest,Uncompressed video
Conference
Volume
Issue
ISSN
15
Pt 1
0302-9743
Citations 
PageRank 
References 
1
0.38
11
Authors
6
Name
Order
Citations
PageRank
Michael Wels112910.56
B. M. Kelm2151.99
Matthias Hammon36712.70
Anna Jerebko416812.37
M Sühling510.38
Dorin Comaniciu68389601.83