Title
Control of Cellular Glycolysis by Perturbations in the Glucose Influx
Abstract
For certain metabolic routes of living organism oscillations in the concentration of the reactant substances appear. During the glycolysis, when the glucose is broken to obtain energy, oscillations can be seen in many steps of the process. These oscillations are damped down, in general, due to the feedback that keeps stable the cellular mechanism. However, certain values of the flux of glucose input keep the oscillations of the metabolic system. In this paper, the influence of a periodic modulation added to the influx of glucose inside the cell in a kinetic model which simulates the glycolysis is analyzed. Simulations of the perturbed glycolytic model exhibit periodic and quasiperiodic behaviors depending on the amplitude and the frequency of the perturbation. The next-maximum maps obtained distinguish between periodic behavior and quasiperiodic one.
Year
DOI
Venue
2008
10.1007/978-3-642-02504-4_12
CIBB
Keywords
DocType
Volume
oscillations,glycolysis
Conference
5488
ISSN
Citations 
PageRank 
0302-9743
0
0.34
References 
Authors
1
3
Name
Order
Citations
PageRank
Jaime Arturo de la Torre100.34
Maria Carmen Lemos232.53
Antonio Córdoba311.38