Name
Title | ||
|---|---|---|
Development of a Quantitative Structure-Activity Relationship Model for Inhibition of Gram-positive Bacterial Cell Growth by Biarylamides. |
Abstract | ||
|---|---|---|
A set of compounds consisting of a new and diverse collection of biarylamides was examined using quantitative structure-activity relationship techniques for the purpose of developing a model to describe inhibition of gram-positive bacterial growth (minimum inhibition concentration). The model was sought in order to obtain insight for designing new molecules. A detailed analysis of the underlying structure-activity relationship helped provide insight concerning which structural features of the molecules modulated the activity of the compounds against gram-positive organisms. |
Year | DOI | Venue |
|---|---|---|
2004 | 10.1021/ci034158p | JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES |
Keywords | Field | DocType |
quantitative structure activity relationship,cell growth | Nanotechnology,Quantitative structure–activity relationship,Bacterial cell structure,Computational chemistry,Bacterial growth,Computational biology,Gram,Mathematics | Journal |
Volume | Issue | ISSN |
44 | 1 | 0095-2338 |
Citations | PageRank | References |
0 | 0.34 | 4 |
Authors | ||
6 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| David T. Stanton | 1 | 101 | 28.81 |
| Prakash J. Madhav | 2 | 0 | 0.34 |
| Larry J. Wilson | 3 | 0 | 0.34 |
| Timothy W. Morris | 4 | 10 | 1.14 |
| Paul M. Hershberger | 5 | 0 | 0.34 |
| Christian N. Parker | 6 | 19 | 2.03 |