Title | ||
---|---|---|
Measurement of cell and bacterial activity using array-based ISFET Chemical Current-Conveyor in weak-inversion |
Abstract | ||
---|---|---|
The ISFET chemical current conveyor (CCCII+) was first reported by the authors at ISCAS 2008. In this paper a new application of the CCCII+ is presented, namely to provide a direct means of measuring cell and bacterial activity. The measurement system is based on an array of unmodified ISFET CCCII+ sensors each of which when operated in weak inversion gives an output corresponding to the time derivative of hydrogen ions. Combining each of the CCCII+ time derivative outputs in the array using the analog computational versatility of the CCCII+ current output stage provides a signal corresponding to cell and bacterial activity. The design has been fully simulated using Triple-well 0.18-μm CMOS technology and the results presented in this paper show that a viable system for direct measurement of cell and bacterial activity can be obtain, further confirming the utility of the CCCII+ for another biochemical sensing application. |
Year | DOI | Venue |
---|---|---|
2012 | 10.1109/ISCAS.2012.6271687 | ISCAS |
Keywords | Field | DocType |
iscas 2008,biosensors,cmos integrated circuits,hydrogen ions,current output stage,unmodified isfet cccii+ sensor array,triple-well cmos technology,weak-inversion operation,microorganisms,biochemical sensing application,analog computational versatility,size 0.18 mum,ion sensitive field effect transistors,chemical sensors,bacterial activity measurement,cell measurement,array-based isfet chemical current-conveyor,time derivative outputs,current conveyors,sensor arrays,capacitors,chemicals,impedance,sensors | ISFET,Capacitor,System of measurement,Computer science,Electronic engineering,Electrical impedance,CMOS,Time derivative,Biosensor,Current conveyor | Conference |
ISSN | ISBN | Citations |
0271-4302 | 978-1-4673-0218-0 | 0 |
PageRank | References | Authors |
0.34 | 2 | 5 |
Name | Order | Citations | PageRank |
---|---|---|---|
Panavy Pookaiyaudom | 1 | 1 | 0.82 |
Apisak Worapishet | 2 | 85 | 20.67 |
F. J. Lidgey | 3 | 13 | 10.51 |
Khaled Hayatleh | 4 | 10 | 12.62 |
Christofer Toumazou | 5 | 265 | 59.06 |