Name
Abstract | ||
|---|---|---|
IP6 Kinases (IP6Ks) are important mammalian enzymes involved in inositol phosphates metabolism. Although IP6Ks have not yet been identified in plant chromosomes, there are many clues suggesting that the corresponding gene might be found in plant mtDNA, encrypted and hidden by virtue of editing and/or trans-splicing processes. In this paper, we propose an approach to search for the gene IP6K and applied it on mitocondrial DNA (mtDNA) of plants. To search for the gene IP6K, we applied a technique based on motif discovery by considering the nucleotide sequence corresponding to a specific tag of the IP6K family. Such a tag has been found in all IP6K genes identified up to now, as well as in all genes belonging to the Inositol Polyphosphates Kinases (IPK) superfamily. IPK tag sequence corresponds to the catalytic site of the enzyme and it can be considered as an identifier of IPK genes. The analysis we conducted provided the relevant negative answer that IP6K does not actually occur in vegetable mtDNA. Finally, we also validated our approach by searching for the known Ipk1 gene in Arabidopsis thaliana genome. |
Year | DOI | Venue |
|---|---|---|
2010 | 10.1007/978-3-642-21946-7_5 | CIBB |
Keywords | Field | DocType |
ipk gene,plant mtdna,corresponding gene,ip6k gene,ipk1 gene,ipk tag sequence corresponds,specific tag,ip6k gene discovery,ip6k family,vegetable mtdna,gene ip6k | Genome,Gene,Inositol,Binding site,Biology,Nucleic acid sequence,Kinase,Arabidopsis thaliana,Mitochondrial DNA,Bioinformatics,Genetics | Conference |
Volume | ISSN | Citations |
6685 | 0302-9743 | 0 |
PageRank | References | Authors |
0.34 | 6 | 5 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Fabio Fassetti | 1 | 223 | 22.68 |
| Ofelia Leone | 2 | 0 | 1.35 |
| Luigi Palopoli | 3 | 1387 | 185.69 |
| Simona E. Rombo | 4 | 192 | 22.21 |
| Adolfo Saiardi | 5 | 0 | 1.01 |