Title
Dual-model automatic detection of nerve-fibres in corneal confocal microscopy images
Abstract
Corneal Confocal Microscopy (CCM) imaging is a non-invasive surrogate of detecting, quantifying and monitoring diabetic peripheral neuropathy. This paper presents an automated method for detecting nerve-fibres from CCM images using a dual-model detection algorithm and compares the performance to well-established texture and feature detection methods. The algorithm comprises two separate models, one for the background and another for the foreground (nerve-fibres), which work interactively. Our evaluation shows significant improvement (p ≅ 0) in both error rate and signal-to-noise ratio of this model over the competitor methods. The automatic method is also evaluated in comparison with manual ground truth analysis in assessing diabetic neuropathy on the basis of nerve-fibre length, and shows a strong correlation (r = 0.92). Both analyses significantly separate diabetic patients from control subjects (p ≅ 0).
Year
Venue
Keywords
2010
MICCAI
algorithms,signal to noise ratio,feature detection,error rate,confocal microscopy,artificial intelligence,ground truth
Field
DocType
Volume
Computer vision,Feature detection,Pattern recognition,Gabor wavelet,Computer science,Ophthalmoscopy,Word error rate,Ground truth,Discrete wavelet transform,Artificial intelligence,Diabetic neuropathy,Confocal microscopy
Conference
13
Issue
ISSN
ISBN
Pt 1
0302-9743
3-642-15704-1
Citations 
PageRank 
References 
3
0.45
8
Authors
5
Name
Order
Citations
PageRank
M. A. Dabbah1153.59
Jim Graham2200132.51
I. Petropoulos381.37
M. Tavakoli430.45
R. A. Malik561.10