Title
Publication Bias in Neuroimaging Research: Implications for Meta-Analyses.
Abstract
Neuroimaging and the neurosciences have made notable advances in sharing activation results through detailed databases, making meta-analysis of the published research faster and easier. However, the effect of publication bias in these fields has not been previously addressed or accounted for in the developed meta-analytic methods. In this article, we examine publication bias in functional magnetic resonance imaging (fMRI) for tasks involving working memory in the frontal lobes (Brodmann Areas 4, 6, 8, 9, 10, 37, 45, 46, and 47). Seventy-four studies were selected from the literature and the effect of publication bias was examined using a number of regression-based techniques. Pearson’s r correlation coefficient and Cohen’s d effect size estimates were computed for the activation in each study and compared to the study sample size using Egger’s regression, Macaskill’s regression, and the ‘Trim and Fill’ method. Evidence for publication bias was identified in this body of literature (p < 0.01 for each test), generally, though was neither task- nor sub-region-dependent. While we focused our analysis on this subgroup of brain mapping studies, we believe our findings generalize to the brain imaging literature as a whole and databases seeking to curate their collective results. While neuroimaging databases of summary effects are of enormous value to the community, the potential publication bias should be considered when performing meta-analyses based on database contents.
Year
DOI
Venue
2012
10.1007/s12021-011-9125-y
Neuroinformatics
Keywords
Field
DocType
Brain imaging, fMRI, Databases, Meta-analysis, Publication bias
Social psychology,Brain mapping,Working memory,Cognitive psychology,Artificial intelligence,Neuroimaging,Publication bias,Functional magnetic resonance imaging,Psychology,Meta-analysis,Machine learning,Sample size determination,Meta-Analysis as Topic
Journal
Volume
Issue
ISSN
10
1
1559-0089
Citations 
PageRank 
References 
3
0.54
14
Authors
2
Name
Order
Citations
PageRank
Robin Jennings130.54
John D Van Horn231628.50